Executive function and type 2 diabetes: putting the pieces together.
نویسندگان
چکیده
The devastating impact of type 2 diabetes mellitus (DM) on vascular, renal, retinal, and peripheral nerve functions has been well documented. However, there is also evidence that older adults with this disease exhibit impairments in the planning, coordinating, sequencing, and monitoring of cognitive operations, collectively known as executive function. Although poorly understood, disturbances in executive function, particularly within the dimension of time sharing, may contribute to the gait abnormalities and increased risk for falls, functional impairments, and disabilities associated with type 2 DM. However, the relationships between executive function and functional abilities remain poorly understood in this population. Current neuropsychological research regarding the concept of executive function is presented here as a framework upon which to examine the integrity of this critical cognitive entity in adults with type 2 DM. The pathophysiological mechanisms thought to underlie diabetes-related executive dysfunction are explored, and the possible contributions of executive deficits to impairments in gait and function observed in older people with type 2 DM are summarized. Finally, a brief discussion of dual-task assessment and intervention strategies that may facilitate the care and rehabilitation of the growing population of patients with type 2 DM is provided.
منابع مشابه
Ghrelin is a possible new predictor associated with executive function in patients with type 2 diabetes mellitus
AIMS/INTRODUCTION The aim of the present research was to study the ghrelin level, executive function and their possible association in patients with type 2 diabetes mellitus. MATERIALS AND METHODS A total of 370 people were recruited between March 2015 and March 2016 in this study. Among them, 212 participants were patients with type 2 diabetes mellitus and 158 participants were included as t...
متن کاملExecutive cognitive impairment detected by simple bedside testing is associated with poor glycaemic control in type 2 diabetes.
AIMS Cognitive impairment in people with type 2 diabetes is a barrier to successful disease management. We sought to determine whether impaired executive function as detected by a battery of simple bedside cognitive tests of executive function was associated with inadequate glycaemic control. METHODS People with type 2 diabetes attending a tertiary referral diabetic clinic who consented to pa...
متن کاملAcute Hypoglycemia Impairs Executive Cognitive Function in Adults With and Without Type 1 Diabetes
OBJECTIVE Acute hypoglycemia impairs cognitive function in several domains. Executive cognitive function governs organization of thoughts, prioritization of tasks, and time management. This study examined the effect of acute hypoglycemia on executive function in adults with and without diabetes. RESEARCH DESIGN AND METHODS Thirty-two adults with and without type 1 diabetes with no vascular co...
متن کاملThe effect of high-intensity interval training on cognitive and memory impairments in obesity and diabetes: A review study
The effect of high-intensity interval training on cognitive and memory impairments in obesity and diabetes: A review study Background and Aim nowadays, industrialization has reduced physical activity and lifestyle changes, resulting in the spread of lifestyle-related diseases. A common feature in most diseases associated with the new lifestyle is obesity. Obesity as a multifactorial disease i...
متن کاملCharacteristics of neuropsychological functions in inpatients with poorly‐controlled type 2 diabetes mellitus
UNLABELLED Aims/Introduction: It has been suggested that type 2 diabetes is associated with cognitive impairment. We investigated the neuropsychological profile of inpatients with poorly controlled type 2 diabetes and assessed the effects of clinical factors on neuropsychological functions. MATERIALS AND METHODS Forty-two patients with type 2 diabetes and 32 non diabetic control subjects w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Physical therapy
دوره 92 3 شماره
صفحات -
تاریخ انتشار 2012